Smoke or Cannabis-Related Businesses in Knoxville, Tennessee 2026
Cannabis in Knoxville
Knoxville, the gateway to the Great Smoky Mountains and home to the University of Tennessee, supports a CBD and smoke shop market within the state's restrictive framework. The city's college-town energy and proximity to one of America's most visited national parks create demand for accessories and hemp products.
The Hive
DispensariesKnoxville, Tennessee
★★★★★
Apotheca - Knoxville - Cumberland
DispensariesKnoxville, Tennessee
★★★★★
Apotheca - Knoxville - Kingston Pike
DispensariesKnoxville, Tennessee
★★★★★Roots and Releaf
DispensariesKnoxville, Tennessee
★★★★★Kiley's Buds N Stuff LLC Dispensary.
DispensariesKnoxville, Tennessee
★★★★★Dr.SMOKE SHOP
Smoke ShopKnoxville, Tennessee
★★★★★MarbleCity Vapor/Smoke Shop
Smoke ShopKnoxville, Tennessee
★★★★★Fire in the Hole
Ancillary ServicesKnoxville, Tennessee
★★★★★Sweet Leaf Hemp Farms - Division of Sweet Leaf Dist & Whls
Ancillary ServicesKnoxville, Tennessee
★★★★★Hemp House
CBD StoreKnoxville, Tennessee
★★★★★Pure Smoke CBD & Wellness
CBD StoreKnoxville, Tennessee
★★★★★CBD Plus USA
CBD StoreKnoxville, Tennessee
★★★★★Realbudz Dispensary - Knoxville
DispensariesKnoxville, Tennessee
★★★★★Apotheca Cannabis Dispensary
DispensariesKnoxville, Tennessee
★★★★★Appalachian Natural Cannabis Co.
Cannabis BrandKnoxville, Tennessee
★★★★★Clouds Over Knox
HeadshopKnoxville, Tennessee
★★★★★Smoke Shop
Smoke ShopKnoxville, Tennessee
★★★★★My Canna Buds
Ancillary ServicesKnoxville, Tennessee
★★★★★Chapman Highway Hemp Solutions
Hemp BusinessKnoxville, Tennessee
★★★★★Smoke Rings Smoke Shop
Smoke ShopKnoxville, Tennessee
★★★★★
CBD American Shaman Knoxville Tn
DispensariesKnoxville, Tennessee
CBD American Shaman- Bearden
DispensariesKnoxville, Tennessee
Smoke Shops in Knoxville
Knoxville's smoke shops near the UT campus on the Strip, along Kingston Pike, and in the Old City carry CBD products, accessories, and hemp items.
Knoxville Cannabis Rules
Tennessee: CBD only, marijuana illegal. See our Tennessee regulations page.
Branded Products for Knoxville
Knoxville smoke shops can connect with the Volunteer State market through branded products from Cannabis Promotions — custom grinders, logo accessories, and university-area-friendly merchandise.