Smoke or Cannabis-Related Businesses in Columbia, South Carolina 2026

Short answer: Columbia, South Carolina has 19 smoke or cannabis-related businesses listed for 2026. Compliance rules are set by the South Carolina regulator.

Cannabis in Columbia

Columbia, South Carolina's state capital and home to the University of South Carolina, is where the state's cannabis policy debate plays out. While the legislature has considered medical marijuana bills, the state remains without any legal cannabis program. Columbia's smoke shop and CBD market serves the capital city's diverse population of students, government workers, and military families.

101 Smoke Shop - Columbia - Senate St. — Smoke Shop in Columbia, SC

101 Smoke Shop - Columbia - Senate St.

Columbia, South Carolina

★★★★★5.0(Google)

Your CBD Store | SUNMED - Columbia, SC — CBD Store in Columbia, SC

Your CBD Store | SUNMED - Columbia, SC

Columbia, South Carolina

★★★★★5.0(Google)

Midland CBD and Oils — CBD Store in Columbia, SC

Midland CBD and Oils

Columbia, South Carolina

★★★★★5.0(Google)

Redeem Therapeutics — Hemp Business in Columbia, SC

Redeem Therapeutics

Columbia, South Carolina

★★★★★5.0(Google)

Illuminati Glass Gallery & Smoke Shop — Smoke Shop in Columbia, SC

Illuminati Glass Gallery & Smoke Shop

Columbia, South Carolina

★★★★★4.9(Google)

Your CBD Store | SUNMED - Irmo, SC — CBD Store in Columbia, SC

Your CBD Store | SUNMED - Irmo, SC

Columbia, South Carolina

★★★★★4.9(Google)

CannaBliss Farmacy — Dispensaries in Columbia, SC

CannaBliss Farmacy

Columbia, South Carolina

★★★★★4.8(Google)

Seven Sense Intl Smoke & Vape — Headshop in Columbia, SC

Seven Sense Intl Smoke & Vape

Columbia, South Carolina

★★★★★4.8(Google)

Crowntown Cannabis at Five Points — Consumption Lounge in Columbia, SC

Crowntown Cannabis at Five Points

Consumption Lounge

Columbia, South Carolina

★★★★★4.8(Google)

Essential Vapors & CBD Store of Lexington — Hemp Business in Columbia, SC

Essential Vapors & CBD Store of Lexington

Columbia, South Carolina

★★★★★4.8(Google)

Razz Smoke & Vape — Smoke Shop in Columbia, SC

Razz Smoke & Vape

Columbia, South Carolina

★★★★★4.7(Google)

High Life Smoke Shop — Smoke Shop in Columbia, SC

High Life Smoke Shop

Columbia, South Carolina

★★★★★4.7(Google)

The Bizarre Bazaar Smoke & Vape — Headshop in Columbia, SC

The Bizarre Bazaar Smoke & Vape

Columbia, South Carolina

★★★★★4.7(Google)

Veteran Vapors — Hemp Business in Columbia, SC

Veteran Vapors

Columbia, South Carolina

★★★★★4.6(Google)

Kure CBD & Vape — Hemp Business in Columbia, SC

Kure CBD & Vape

Columbia, South Carolina

★★★★★4.6(Google)

CBD Farmacy of Columbia — CBD Store in Columbia, SC

CBD Farmacy of Columbia

Columbia, South Carolina

★★★★★4.5(Google)

Garner's Natural Life Columbia — Hemp Business in Columbia, SC

Garner's Natural Life Columbia

Columbia, South Carolina

★★★★★4.5(Google)

Jay's Vape and Wellness Center — Smoke Shop in Columbia, SC

Jay's Vape and Wellness Center

Columbia, South Carolina

★★★★☆4.4(Google)

Thomas’s Cannabis Affiliate Investors Group — Dispensaries in Columbia, SC

Thomas’s Cannabis Affiliate Investors Group

Columbia, South Carolina

★★★☆☆3.3(Google)

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Smoke Shops in Columbia

Columbia's smoke shops and CBD stores along Assembly Street, Devine Street, and near the USC campus carry accessories, hemp products, and CBD items.

Columbia Cannabis Rules

South Carolina has no cannabis program. All marijuana is illegal. Hemp CBD is available. See our South Carolina regulations page.

Branded Products for Columbia

Columbia smoke shops can grow with branded products from Cannabis Promotions — custom grinders, logo accessories, and promotional merchandise.

Listings & accuracy: Business listings are aggregated from public sources and user submissions and may be inaccurate, incomplete, or out of date. Inclusion is not an endorsement, and Cannabis Promotions does not independently verify the licensing or legal status of listed businesses — always confirm directly with the business and the relevant state or provincial regulator. Reviews reflect the views of their authors, not Cannabis Promotions.

Not professional advice: Content is provided for general informational purposes only and does not constitute legal, financial, tax, or other professional advice.

Age & products: You must be 21 or older to use this site. Cannabis Promotions provides custom branding, merchandise, and packaging products only — we do not sell, distribute, or facilitate the sale of cannabis, THC, or any controlled substance.