Root 66 Dispensary - South Grand, MO

Root 66 Dispensary - South Grand, MO serves as a recreational and medical dispensary located in St. Louis, Missouri. Situated at 3737 S. Grand Blvd., St. Louis, MO 63118, this St. Louis cannabis business proudly operates within the vibrant South Grand community, renowned locally and regionally as a diverse International District filled with eclectic shops, unique stores, and a wide array of ethnic restaurants. As the first medical marijuana dispensary to open in the City of St. Louis, Root 66 welcomes adults 21 and older, as well as medical patients 18 and older holding a valid medical marijuana card.

Inside the St. Louis dispensary, customers and patients discover a wide variety of cannabis products, including cannabis flower, vapes, concentrates, edibles, beverages, and more. The dedicated team, led by Store Manager Patrick Topping—who brings a background from the local craft beer industry—helps visitors navigate the extensive selection and find products that suit their preferences. Open every day to serve the local community, Root 66 Dispensary - South Grand, MO provides convenient online ordering ahead for both recreational and medical shoppers seeking quality cannabis in St. Louis.

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